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Miller LePrell

Hearing Loss

Hearing loss is one of the most prevalent disabling conditions in the industrialized world, adversely affecting an individual’s physical, cognitive, behavioral and social functions.  A total of 39 million Americans and 44 million Europeans have clinically significant hearing loss, with one third of this hearing loss coming from exposure to loud noise.  Such exposure occurs in both work and recreational activities, and can adversely affect an individual’s physical, cognitive, behavioral and social functions.  Awareness of noise-induced hearing loss (NIHL) issues within the United States has been increasing due to decades of government-mandated hearing conservation and educational programs within military and industrial environments, and an improved understanding of general health issues.  Studies by NIOSH demonstrate that half of US adults believe they have suffered some form of hearing loss, including 35% of 18 to 29 year olds, and that 48% of all adults understand hearing loss is not solely due to the aging process. click here for more

Company Background

OtoMedicine, Inc., is a new biopharmaceutical company, founded in 2006, to commercialize more than two decades of scientific research and technology developed in the laboratories of Dr. Josef Miller at the University of Michigan’s Kresge Hearing Research Institute.  OtoMedicine’s mission is to become the leading provider of medicines to prevent, treat, and cure hearing loss.  Its initial focus is to amplify, in a compelling manner, the evidence it has already gathered to demonstrate that a proprietary combination of compounds can dramatically reduce noise-induced hearing loss (NIHL), one of the most prevalent disabling conditions in the industrialized world and for which there is no FDA-approved means of treatment.  Called AuraquellTM, this specific combination of micronutrients has already been shown to provide significant synergistic protection against noise-induced injury in pre-clinical studies with animal subjects.  In other words, the protection resulting from administration of the combination was greater than that following any of the ingredients individually.  Based on the dramatic protection observed in pre-clinical studies, this formulation is expected to be a highly effective therapy for prevention of NIHL in humans. click here for more

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